Home > Volume XIV




                                 Prague Castle


Prague Castle, founded in 870 AD, is the largest medieval castle in Europe. It was the seat of the Kings of Bohemia for centuries, and today the President of the Czech Republic rules from here. It history dates back to the 9th century when the first known building was erected on the site. In the 12th century, it was replaced by a Romanesque palace and in the 14th century it was rebuilt in the Gothic style under the reign of Charles IV. After WWI, renovations to the castle buildings and to the gardens were undertaken by architect, J. Plecnik.


The Prague Castle complex covers over 18 acres and is centered around three great courtyards. The dominant building within, and the most recognizable landmark in the city is St. Vitus Cathedral. Destructive wars and fires (and subsequent renovations), along with differing political forces have combined to create an intriguing mix of churches, palaces, great halls, fortifications, viewing towers, museums, art galleries, cafes, a monastery and Golden Lane. Today, Prague Castle serves as the historical and politcal centre for both city and state. A Changing of the Guard ceremony takes place every hour at the front gates.





In This Issue


  • Copper Linked To Alzheimer's Disease
  • The Five Most Controversial Decisions Alzheimer's Caregivers Will Ever Face
  • Study Suggest Iron Is Core Of Alzheimer's Disease
  • Sniffing Out New Strategies In The Fight Against Alzheimer's Disease
  • Alzheimer's Store Featured Product
  • Recipe Of The Week
  • Newsletter Promotions
  • Events Calendar
  • Trivia Questions



Editorial Note: Healthcare Products LLC reviews the news wires looking for press releases and current articles relating to dementia. We write a brief description of each article and by clicking on its heading will bring you to the originally written story ...hope you enjoy The Alzheimer's News...

Copper Linked To Alzheimer's Disease


(Source: BBC News Health) -  A lifetime of too much copper in our diets may be contributing to Alzheimer's disease, US scientists say. 

However, research is divided, with other studies suggesting copper may actually protect the brain. 
The latest study in Proceedings of the National Academy of Sciences showed high levels of copper left the brain struggling to get rid of a protein thought to cause the dementia.
Copper is a vital part of our diet and necessary for a healthy body.
Tap water coming through copper pipes, red meat and shellfish as well as fruit and vegetables are all sources of dietary copper.
The study on mice, by a team at the University of Rochester in New York, suggested that copper interfered with the brain's shielding - the blood brain barrier. 
Mice that were fed more copper in their water had a greater build-up of the metal in the blood vessels in the brain. 
The team said this interfered with the way the barrier functioned and made it harder for the brain to get rid of a protein called beta amyloid.
One of the hallmarks of Alzheimer's disease is the formation of plaques of amyloid in the dying brain. 
Lead researcher Dr Rashid Deane said: "It is clear that, over time, copper's cumulative effect is to impair the systems by which amyloid beta is removed from the brain."

Study Suggest Iron Is Core Of Alzheimer's Disease


(Source: Medical Press) - Alzheimer's disease has proven to be a difficult enemy to defeat. After all, aging is the No. 1 risk factor for the disorder, and there's no stopping that.


Most researchers believe the disease is caused by one of two proteins, one called tau, the other beta-amyloid. As we age, most scientists say, these proteins either disrupt signaling between neurons or simply kill them.
Now, a new UCLA study suggests a third possible cause: iron accumulation.
Dr. George Bartzokis, a professor of psychiatry at the Semel Institute for Neuroscience and Human Behavior at UCLA and senior author of the study, and his colleagues looked at two areas of the brain in patients with Alzheimer's. They compared the hippocampus, which is known to be damaged early in the disease, and the thalamus, an area that is generally not affected until the late stages. Using sophisticated brain-imaging techniques, they found that iron is increased in the hippocampus and is associated with tissue damage in that area. But increased iron was not found in the thalamus.
The research appears in the August edition of the Journal of Alzheimer's Disease.


The Five Most Controversial Decisions Alzheimer's Caregivers Will Ever Face


(Source: Huff Post) - 1. Should the Person Stop Driving?
Late one evening, I was deeply immersed in editing the photographs I'd taken at the Cincinnati Zoo that day when I was startled by the phone ringing. I thought it was probably Ed, my Romanian life partner and soul mate. 
But it wasn't. It was a sweet female voice I didn't recognize calling to tell me she'd found Ed driving on the wrong side of the road. He'd pulled over and so she'd stopped too, and seeing how confused he was, she offered him a ride home. 
Suddenly, I realized the cold hard truth: He could no longer drive safely. My heart sank and I told him very quietly that he had to stop driving. 
Sooner or later, driving becomes a problem for all people with Alzheimer's. There are usually many warning signs that it is no longer safe for them to be driving. The Alzheimer's Association lists five primary ones: 
•Forgetting how to locate familiar places
•Failing to observe traffic signs
•Making slow or poor decisions in traffic
•Driving at an inappropriate speed
•Becoming angry or confused while driving
I would add two obvious items to this list: Causing an accident or running into another car while parking.
When loved ones exhibit one or more of these, it's time to get them to stop driving. This will be one of the most difficult actions you will ever have to take. We all cherish the independence of being able to drive anywhere we want -- any time we want -- and people with Alzheimer's are no exception.
It's highly likely that you will face all manner of resistance, but you are ultimately responsible for getting the person to stop driving, one way or another.
(Source: Yahoo News) - The newest chemical under investigation for managing Alzheimer’s disease (AD) is actually not new at all. Insulin, the therapeutic hormone all-too familiar to individuals with diabetes, has been around for decades. In fact December will mark 90 years since its discoverers earned the Nobel Prize in Physiology or Medicine for the extraction of insulin for clinical use. Yet to say that insulin has been under our noses all these years wouldn’t exactly be correct. Because if it had been under our noses, we might have sensed its neurologic benefits sooner.
The latest insulin therapy is not delivered via injection like its diabetes-treating counterparts, nor does it come in the form of a pill or a patch like the cholinesterase inhibitors often prescribed to patients with AD. Instead this novel therapeutic enters the body through the nose—the only entry point that gives insulin a chance of reaching the brain.
A large peptide molecule, insulin from the blood cannot float easily into the brain because the blood brain barrier (BBB), a sort of neuroprotective moat, prevents its transport. Fortified by cellular guards called tight junctions, the BBB rejects many pharmacologic hopefuls, allowing entrance only to certain types of substances. Namely small or lipophilic molecules can be administered orally (or via injection, or through the skin) and as long as the relevant chemicals end up in the blood stream, they can casually saunter across the BBB and act on the brain. Large and cumbersome, insulin does not have this luxury and must therefore take a more creative route across the moat.


The Alzheimer's Store Featured Product!




Item #0077 Dial-less Telephone


Looks like a regular phone but has no numbers to dial!


Recipe Of The Week      
Spicy Southwest flavors pair with sweet and tangy pickled red onions to create a standout turkey burger. (The pickled onions would also be great with this burger.) Make it a meal: Serve with Southwestern Calico Corn or sweet potato fries and a frosty lager.

Spicy Turkey Burgers With Pickled Onions


For Pickled onions:  
1 cup  red-wine vinegar  
2 tablespoons  packed brown sugar  
1/2 teaspoon  salt  
1/4 teaspoon  ground allspice  
1   small red onion, halved and very thinly sliced  
For Burgers:  
1 pound  93%-lean ground turkey  
2 tablespoons  chopped fresh cilantro  
1 1/2 teaspoons  ground cumin  
1/2 teaspoon  ground chipotle pepper  
1/2 teaspoon  salt  
1/8 teaspoon  ground allspice  
1 teaspoon  canola oil  
4   whole-wheat buns, split  
8 teaspoons  reduced-fat mayonnaise, divided  
To prepare pickled onions: Whisk vinegar, brown sugar, salt and allspice in a medium glass bowl. Microwave on High until the mixture boils, 2 to 3 minutes. (Alternatively, bring the mixture to a boil in a small saucepan on the stove). Add onions and toss to coat.
To prepare burgers: Preheat grill to high. Place turkey in a medium bowl and gently mix in cilantro, cumin, ground chipotle, salt and allspice until distributed throughout the meat. Form the mixture into 4 patties. Brush with oil.
Grill the burgers until cooked through and no longer pink in the center, 3 to 4 minutes per side. Meanwhile, toast buns on the grill, if desired.
Drain the onions, discarding the marinade. Spread 2 teaspoons mayonnaise on each bun; top with a burger and pickled onions. 

Newsletter Promotions - Enjoy 15% Off Of The Following Products..

Available Only To Subscribers..   **check product reviews on our blog....




Events Calendar: (if you would like to list your upcoming event, email us at contact@alzstore.com)

Aug 27th - 1:00-2:00 pm Alzheimer's/Dementia Support Group / Waukesha, WI

Aug 27th - 5:00-7:00 pm - Dine To End Alzheimer's / Willow Park, TX

Aug 27th - 5:30-7:30 pm  - Alzheimer's Summer Fling Fundraiser / Hamilton, NJ

Aug 28th - 5:00-8:00 pm CDT - Fun-Raiser To SupportAlzheimer's Association / Schaumburg, IL

Aug 30th - 7:00 pm Trivia Night / Desloge, MO




Take a guess at these trivia questions ..answers will be posted in next week's newsletter

1. Which singer joined Mel Gibson in the movie, Mad Max: Beyond The Thunderdome?
2. On TV, who did the character Lurch work for?
3. How many tentacles does a squid have?

**email your answers to contact@alzstore.com to be in the running for a free gift! Winner will be chosen at random at the beginning of the month...

Answers to last week's trivia; Cathode Ray Tube / Platypus / Henry Morton Stanley

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