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Hollywood's Greatest Style Icon

In celebration of what would have been Audrey Hepburn's 85th birthday this month, we chose to honor her in this week's news edition. We think you would all agree!!

Actress, fashion icon, and philanthropist Audrey Hepburn was born on May 4, 1929, in Brussels, Belgium. At age 22, she starred in the Broadway production of Gigi. Two years later, she starred in the film Roman Holiday (1953) with Gregory Peck. In 1961, she set new fashion standards as Holly Golightly in Breakfast at Tiffany's. Hepburn is one of the few actresses to win an Emmy, Tony, Grammy, and Academy Award. In her later years, acting took a back seat to her work on behalf of children.

A native of Brussels, Hepburn spent part of her youth in England at a boarding school there. During much of World War II, she studied at the Arnhem Conservatory in The Netherlands. After the Nazis invaded the country, Hepburn and her mother struggled to survive. After the war, Hepburn continued to pursue an interest in dance. She studied ballet in Amsterdam and later in London.

In 1948, Hepburn made her stage debut as a chorus girl in the musical High Button Shoes in London. Hepburn made her feature film debut in 1951's One Wild Oat, in an uncredited role. She took the world by storm in the film Roman Holiday (1953) with Gregory Peck. Audiences and critics alike were wowed by her portrayal of Princess Ann, the royal who escapes the constrictions of her title for a short time. She won the Academy Award for Best Actress for this performance. Hepburn returned to the Broadway stage to star in Ondine with Mel Ferrer.She won the 1954 Tony Award for Best Actress in a Play for her performance. Hepburn and Ferrer got married on September 25, 1954, in Switzerland. Showcasing her dancing abilities, Hepburn starred opposite Fred Astaire in the musical Funny Face (1957). She played Sister Luke in The Nun's Story (1959), which earned her an Academy Award nomination. Her first child, a son named Sean, was born in 1960. Hepburn set new fashion standards as Holly Golightly in Breakfast at Tiffany's (1961). Hepburn and her husband separated and later divorced. She married Italian psychiatrist Andrea Dotti in 1969, and the couple had a son, Luca, in 1970.

She became a goodwill ambassador for UNICEF in the late 1980s. Traveling the world, Hepburn tried to raise awareness about children in need. She understood too well what it was like to go hungry from her days in The Netherlands during the German Occupation. Making more than 50 trips, Hepburn visited UNICEF projects in Asia, Africa, and Central and South America. She won a special Academy Award for her humanitarian work in 1993, but she did not live long enough to receive it. Hepburn died on January 20, 1993, at her home in Tolochenaz, Switzerland after a battle with colon cancer. Her work to help children around the world continues. Her sons, Sean Ferrer and Luca Dotti, along with her companion Robert Wolders, established the Audrey Hepburn Memorial Fund to continue Hepburn's humanitarian work in 1994. It is now known as the Audrey Hepburn Children's Fund.

In This Issue

  • Anti-Aging Factor Offers Brain Boost, Too
  • Investigators Discover How Key Protein Enhances Memory And Learning
  • Professional Gets Personal As Doctor Considers Care Of The Alzheimer's Caregiver
  • How This Maine Woman Could Revolutionize Travel For Older, Rural Mainers
  • Alzheimer's Store Featured Product
  • Recipe Of The Week
  • Newsletter Promotions
  • Events Calendar
  • Trivia Questions
  • Information On Clinical Studies

I believe in manicures. I believe in overdressing. I believe in primping at leisure and wearing lipstick. I believe in pink. I believe happy girls are the prettiest girls. I believe that tomorrow is another day, and... I believe in miracles. - Audrey Hepburn

Editorial Note: Healthcare Products LLC reviews the news wires looking for press releases and current articles relating to Alzheimer's and dementia. We write a brief description of each article and by clicking on its heading will bring you to the originally written story ...hope you enjoy The Alzheimer's News...

Anti-Aging Factor Offers Brain Boost, Too

(Source: Science Daily) - A variant of the gene KLOTHO is known for its anti-aging effects in people fortunate enough to carry one copy. Now researchers find that it also has benefits when it comes to brain function. The variant appears to lend beneficial cognitive effects by increasing overall levels of klotho in the bloodstream and brain.

What's more, the improvements in learning and memory associated with klotho elevation aren't strictly tied to aging. They do occur in aging mice, but also in young animals, according to a report published in the Cell Press journal Cell Reports on May 8th. That means klotho works to enhance brain power, but in an unexpected way.

"Based on what was known about klotho, we expected it to affect the brain by changing the aging process," said Lennart Mucke of the Gladstone Institute and the University of California, San Francisco, who directed the study. "But this is not what we found, which suggests to us that we are on to something new and different."

Aging is a primary risk factor for cognitive decline, lead author Dena Dubal explained. The question was: Would a factor known to play a role in long life have benefits for cognition too?

Professional Gets Personal As Doctor Considers Care Of The Alzheimer's Caregiver

(Source: PBS.Org) - In June 2012, Gary Epstein-Lubow stepped out of a national conference on the topic of patients with Alzheimer’s disease to participate in a smaller, more personal phone meeting on a similar subject: the hospitalization of his mother-in-law, who had recently been diagnosed with dementia.

Epstein-Lubow, a geriatric psychiatrist at Butler Hospital in Providence, R.I., and an assistant professor at Brown University’s Alpert Medical School and School of Public Health, had spent the day hearing about numerous models of care for patients with dementia that, if widely distributed, could change the way families cope with the disease. Now, he faced a grim reality: of the resources developed to help families, none were accessible to his own family members in New Jersey and Rhode Island.

“On a personal level, I was worried,” Epstein-Lubow writes in a stark, personal essay that will be published in April’s edition of Health Affairs. “I was worried about (my father-in-law), my wife, her siblings, and myself. We would be (my mother-in-law)’s caregivers for the rest of her life. And I understood the devastating toll dementia could take on an entire family.”

Investigators Discover How Key Protein Enhances Memory and Learning

(Source: Medical News Today) - Case Western Reserve researchers have discovered that a protein previously implicated in disease plays such a positive role in learning and memory that it may someday contribute to cures of cognitive impairments. The findings regarding the potential virtues of fatty acid binding protein 5 (FABP5) - usually associated with cancer and psoriasis - appear in the The Journal of Biological Chemistry.

"Overall, our data show that FABP5 enhances cognitive function and that FABP5 deficiency impairs learning and memory functions in the brain hippocampus region," said senior author Noa Noy, PhD, a professor of pharmacology at the School of Medicine. "We believe if we could find a way to upregulate the expression of FABP5 in the brain, we might have a therapeutic handle on cognitive dysfunction or memory impairment in some human diseases."

FABP5 resides in many tissues and is especially highly expressed in the brain. Noy and her Case Western Reserve School of Medicine and National Institute on Alcohol Abuse and Alcoholism colleagues particularly wanted to understand how this protein functioned in neurons.

How This Maine Woman Could Revolutionize Travel For Older, Rural Mainers

(Source: Bangor Daily News) - Despite all the advances the United States has made since the first automobiles motored onto the nation’s roadways, the country still doesn’t have a good solution to a big — and growing — problem: lack of access to reliable transportation in rural areas.That is, unless people start thinking differently about the transportation model itself and how it’s funded.

Katherine Freund, 64, of Portland still remembers the exact moment she realized how to make community-based transportation services viable for more people, especially older adults. It was 1989, when she was 39, and she was standing by the window in her living room. It was a sunny day.

A couple of important things had happened before that point, and her mind had been working nonstop. She kept thinking about transportation access.

The previous year, her 3-year-old son had been run over by a car driven by an 84-year-old man with dementia. Instead of being angry, Freund said she recognized the older man was just as much a victim as her son.

The Alzheimer's Store Featured Product!

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Recipe Of The Week
Top pan-grilled sirloin with a soft, savory anchovy-lemon butter and serve with sautéed broccoli rabe for a tasty 20-minute meal. - Recipe From Cooking Light
Grilled Sirloin With Anchovy-Lemon Butter and Broccoli Rabe


Cooking spray
1 (1-pound) boneless sirloin steak
1/2 teaspoon kosher salt, divided
3/8 teaspoon ground black pepper
2 tablespoons unsalted butter
1 1/2 teaspoons grated lemon rind, divided
1 teaspoon fresh lemon juice
1/2 teaspoon anchovy paste
1 teaspoon extra-virgin olive oil
1/4 cup presliced onion
2 garlic cloves, sliced
1/4 teaspoon crushed red pepper
1/2 cup fat-free, lower-sodium chicken broth
8 ounces broccoli rabe (rapini), cut into 1-inch pieces


1. Heat a grill pan over medium-high heat; coat with cooking spray. Sprinkle steak with 1/4 teaspoon salt and 1/4 teaspoon pepper. Add steak to pan; cook for 3 minutes on each side. Let stand 5 minutes. Cut steak across grain into thin slices.
2. Place butter in a bowl. Microwave at HIGH 10 seconds. Add 1/8 teaspoon salt, 1/8 teaspoon pepper, 1/2 teaspoon rind, juice, and anchovy paste; stir until combined. Set aside.
3. Heat a skillet over medium-high heat. Add oil. Add onion; sauté 2 minutes. Add garlic and red pepper; sauté 30 seconds. Stir in broth and rabe; bring to a boil. Cover and simmer 3 minutes. Remove from heat; stir in remaining rind and salt.
4. Place 3 ounces steak and 1/2 cup rabe on each of 4 plates. Top each steak with 1 1/2 teaspoons butter.

Newsletter Promotions - Enjoy 15% Off Of The Following Products..

Available Only To Subscribers...

Events Calendar: (if you would like to list your upcoming event, email us at contact@alzstore.com)

May 12th - 10:30-11:30 am - Alzheimer's Support Group / Frankenmuth, MI

May 13th - 6:30 pm - Alzheimer's Support Group / Fargo, ND

May 14th - 1:30 pm-3:30 pm - Middle Stages Of Alzheimer's / Oconto Falls, WI

May 15th - 7-9:00 am - Purple Pancake Breakfast Fundraiser / Topeka, KS

May 16th - 9:00 am-4:00 pm - Dementia Care Workshop / Columbia, MO

May 19th-22nd - ALFA Conference & Expo / Phoenix, AZ (Alzstore will be there~be sure to visit our booth!)


Take a guess at these trivia questions ..answers will be posted in next week's newsletter

1. Audrey Hepburn played a role as a KLM stewardess in what film?

2. In the 1967 thriller film, 'Wait Until Dark', what character did Audrey play?

3. Which film did Audrey not receive an Oscar nomination?

**email your answers to contact@alzstore.com & include your name & address to be in the running for a free gift! Winner will be chosen at random at the beginning of each month... Thank you for participating in our trivia challenge!!

Answers to last week's trivia; Kent Desormeaux / 4 / Mine That Bird


* The A4 Study is a clinical study for older individuals (ages 65-85) who have normal thinking and memory function but who may be at risk for developing Alzheimer's disease (AD) memory loss sometime in the future. The A4 study is for people without any outward signs of Alzheimer's disease, and is designed to evaluate the effectiveness, safety and tolerability of an investigational drug for AD. The purpose of the Anti-Amyloid Treatment in Asymptomatic Alzheimer’s study (the”A4 study” for short) is to test whether a new investigational treatment can slow the memory loss caused by Alzheimer’s disease. The overall goal of the A4 study is to test whether decreasing amyloid with antibody investigational treatment can help slow the memory loss associated with amyloid buildup in some people. The A4 Study lasts for three years, and participants will be assigned at random to receive either the investigational drug or a placebo and will be monitored over that period. / Learn more...

* NOBLE is a clinical study to evaluate an investigational drug for patients with mild to moderate Alzheimer's disease. Participants will receive the study drug or a placebo. During this study, if you are already taking Aricept or Namenda, you will probably continue to take it along with the study drug or placebo. Studies already done have shown that this investigational drug appears safe. It may work by protecting brain cells which would result in improved memory. But, this has not been proven yet. / Learn more...

* SNIFF - The purpose of the SNIFF study is to find out whether a type of insulin, when administered as a nasal spray, improves memory in adults with a mild memory impairment or Alzheimer’s disease (AD). The rationale behind the study is growing evidence that insulin carries out multiple functions in the brain and that poor regulation of insulin may contribute to the development of AD. Insulin resistance, reduced cerebrospinal fluid insulin levels, and reduced brain insulin signals have been found in AD patients, suggesting that a therapy aimed at correcting these deficiencies may be beneficial. Learn more...

* Trial Match / Learn more...

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