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NBCNews: Women who were reasonably fit when they were middle-aged were much less likely to develop dementia than women who struggled to exercise even a little bit. The fittest women were 90 percent less likely to later develop dementia than those who were the least fit, the team at Gothenburg University in Sweden found. In this case, being highly fit meant everyday exercisers, not athletes. READ MORE
DDDMag: About a year ago, patients in a clinical trial of a Merck Alzheimer’s drug called Verubecestat received a phone call from their memory clinics. “Stop taking the pills and return those left to the clinic immediately,” they were told. “The trial has been cancelled.” My wife and about 1,500 Alzheimer’s patients around the world returned the containers of little blue pills back to their trial physicians. A statistical analysis of the first three years of the study showed there was no chance the drug would work. The test was costing hundreds of millions of dollars with no hope it would ever help patients or come to market. Another promising anti-Alzheimer’s drug had failed. READ MORE
Healio: The use of proton pump inhibitors over a long period did not increase the risk for hip fracture in patients with Alzheimer’s disease, according to new research published in Alimentary Pharmacology & Therapeutics. Sanna Torvinen-Kiiskinen, PhD, of Kuopio Research Centre of Geriatric Care at the University of Eastern Finland, and colleagues wrote that an association between proton pump inhibitor (PPI) use and risk for fractures remains unclear due to contradictory study findings, and their research is the first to look at the potential risk in patients with Alzheimer’s. READ MORE
Neurology Advisor: Alcohol use disorders are a major risk factor for the onset of all types of dementia, particularly early-onset dementia, according to the results of a nationwide retrospective cohort analysis published in the Lancet Public Health. READ MORE
Eurekalert: A study conducted by a multidisciplinary Spectrum Health neurology team has found that dementia patients are not undergoing evaluation at the onset of the dementia process, a delay that prevents early, beneficial treatment. The study also suggests that home-based, patient-centered care may improve early screening and detection of dementia. READ MORE
